Springer Nature. Total protein concentration in tissue homogenates were determined using biuret method Tietz [16]. The animals were randomly distributed into cages and allowed to acclimatize for 2 weeks in a well ventilated room under natural lighting condition. CAS Consumption of medicinal plants has diverse therapeutic benefits and could also have toxic effect. Justicia carnea (belonging to Acanthaceae family) is a flowering plant consisting ~600 species that are widely distributed in the tropics and subtropics [7]. Significant (P<0.05) decrease observed in liver total protein of rat administered with 1200mg/kg of extract could be due to intrinsic factors in-vivo that might not necessarily indicate adverse reaction of the extracts. There are several scientific studies which show that the methanolic leaf extract of Justicia carnea protects the liver from toxic effect of carbon tetrachloride harmful effect on the live integrity and functions. 2005;102(2):197201. This lends the plant some interesting names such as Blood of Jesus plant and Hospital too far. Rich, well-drained soil retaining ample moisture is the perfect home for Brazilian plume flowers. The LD50 of extract was greater than 5000mg/kg body weight. 2007;39(1):4484. Venancio, E. T., Rocha, N. F., Rios, E. R., Feitosa, M. L., Linhares, M. I., Melo, F. H., Matias, M. S., Fonseca, F. N., Sousa, F. C., Leal, L. K., and Fonteles, M. M. Anxiolytic-like effects of standardized extract of Justicia pectoralis (SEJP) in mice: Involvement of GABA/benzodiazepine in receptor. The roots and the leaves possess medicinal values and have been used in treating several diseases. Anaemia is a common blood disorder that affects people of all ages, though people at greater risk are the elderly, young women and infants. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. The plant has various other common names including: Back in the day, the Justicia flower was boiled and used to solve anemia problems. Relative to control, lymphocyte and granulocyte exhibited no significant difference in all doses while MID was elevated in treated groups with significant increase in rats administered with 500 and 800mg/kg body weight. The plant is hardy to USDA Hardiness Zones 8b through 11. Sun M, Zigma S. An improved spectrophotometer assay of superoxide dismutase based on epinephrine autoxidation. When properly cooked with water, the leaf resembles blood, and when milk is added, it turns pink. Leal, L. K., Ferreira, A. Create a beautiful garden with this colorful and Use our interactive toolsto design your dream garden. The presence of blood boosting nutrients such as iron, copper, zinc and vitamin C can help prevent iron-deficiency anaemia and other anemic conditions. Rats that received 50 and 100mg/kg body weight JCEE showed significant (p<0.05) increase in liver weight while other doses showed no significant difference compared to the control. View abstract. 2003;66:1499503. However, further research needs to done to determine the mode of action of the plant, and it's effects on humans. 2013;3(4):1248 https://doi.org/10.7324/JAPS.2013.3422. Google Scholar. Check these Great Plant Combination Ideas with Justicia, Eye-Catching Retaining Walls and Staircases, An Eye-Catching Mediterranean Garden with Agave, Aloe and Pincushion, A Striking Water-Wise Border with Agave, Cactus and Ocotillo, A Beautiful Duo with Agave 'Blue Flame' and 'Blue Glow', A Long-Lasting Summer Garden Idea with Marigold and Sage, 8, 9, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, H1, H2. 4. Fresh leaves of Justicia carnea were collected from Okitipupa area Ondo State. Tissues were processed automatically using automatic tissue processor (Leica TP 1020) and allowed to pass through varying percentage of alcohol and absolute alcohol for the purpose of dehydration following dewaxing in Xylene for 15mins. When it comes to blood boosting and treatment of anemia, justicia carnea has proven beyond doubt to be an effective remedy. The leaves of justicia carnea possess high content of iron and vitamin C. This compounds may be responsible for the blood boosting property of ewe eje leaves. Akintimehin is a lecturer in the Biochemistry unit of Chemical Sciences Department, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. View abstract. The concentration of reduced glutathione content of the tissues was estimated according to Sedlak and Lindsay [19] method. The gradual decrease in the weight of organs following short-term exposure of J. carnea leaf ethanol extract may be attributed to adaptive response of the organs arising from daily dosage of the extract or its metabolites within their body. It helps in replenishing blood lost during period. Materials and Methods Plant material Justicia carnea leaves used in this study were collected from Ozalla Isuofia in Anambra State and identified by Mr. Ozioko These compounds beyond boosting your blood concentration, thereby enhancing the transport of nutrients to various parts of the body, also boost your immune system against several infectious diseases. The protein content may help in cellular functions and are building blocks for structural and functional biomolecules. Decoction of ewe eje or its leaf extract can lower serum cholesterol and get rid of bad cholesterol (LDL). CAS To use the website as intended please At this time there is not enough scientific information to determine an appropriate range of doses for Justicia pectoralis. Tissues were stained with haematoxylin and eosin, mounted on glass slides and examined under a standard light microscope. Not sure which Justicia to pick?Compare All Justicia. Paradoxically, oxidation of GSH has been reported to occur when GSH interact with metal ions thereby generating superoxide anions from the transfer of electrons from the metal ions to molecular oxygen [32]. Previously, J. carnea leaf has been reported to contain high quantity of phytochemical constituents (such as saponins, alkaloids and terpenoids), vitamins (A, C and E) and minerals [9, 10]. It is cultivated and sold as a decorative potted plant and is planted in landscaping as a feature plant in warm . A total number of forty two (42) male albino rats weighing between 120 and 170g were used in this study. To create additional collections, you must be a paid member of our site. For a few weeks, the cutting should be watered every day to promote root development. J Ethnopharmacol. Treatments of experimental animals were in accordance with the Principle of Laboratory Animal Care manual guide of National Institute of Health [14] as approved by the Institution Research Ethics committee. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. The appropriate dose of Justicia pectoralis depends on several factors such as the user's age, health, and several other conditions. They look terrific in properly shaded outside areas such as porches, patios, driveways, and entryways. In these groups, from mild to severe order; shows observable congested portal vein, the liver parenchyma showed area of harmorrhage, the morphology of the hepatocytes appear pyknotic, some show mild fat infiltration (red arrow) the sinusoids appear fibrotic with infiltration of inflammatory red cells (red arrow). what are the pros and cons of testosterone replacement therapy? Anthonia OC, Ikechukwu UR, Uzoma NO, Sunday ELU. Blooming from early summer to fall, the flowers are attractive to hummingbirds and butterflies. 1958;25(1):192205. long (25 cm), and showy flower plumes, 8 in. Justicia carnea does not cause miscarriage or congenital birth defects. Ewe eje is mainly given to persons who want a blood boost such as pregnant women, persons suffering from anemia and other convalescents. All analyzed dataset to support the conclusions of this article is included as tables in the uploaded supplementary files. Akintimehin, E.S., Karigidi, K.O., Omogunwa, T.S. Relative to the control, liver of rats treated with doses of J. carnea ethanol extract showed varied degree of hepatic injury in a dose dependent manner. Luckily, the unique flowers of Jacobinia carnea and its foliage are free from major pest and disease concerns. 2002;82:197205. Karigidi is a lecturer in the Biochemistry unit of Chemical Sciences Department, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. Saunders; 1995. p. 26873. Biochem Pharmacol. Side effects of Ewe eje (Justicia carnea leaf Side Effects) Ewe eje is safe and healthy for consumption. Medapa S, Singh GRJ, Ravikumar V. The phytochemical and antioxidant screening of Justicia wynaadensis. 2017;16(2):21730 https://doi.org/10.17306/J.AFS.2017.0492. Justicia pectoralis seems to have antibacterial and anti-inflammatory effects. Sample (or standard solution) (0.01ml) was mixed with diluted (1:4v/v distilled water) biuret reagent (100mM sodium hydroxide, 16mM sodium-potassium tartrate, 15mM potassium iodide and 6mM copper sulphate). It also increases good cholesterol levels. Ewe eje as it is fondly called by the Westerners in Nigeria is a plant known for its blood boosting abilities. 2). White blood cell counts usually increases following foreign invaders (pathogens) resulting in normal body physiological response which boost the bodys defense mechanisms [28, 29]. Section of livers and kidneys were excised and fixed in 10% formalin for histopathology examination. Effects of kolaviron on hepatic oxidative stress in streptozotocin induced diabetes. Safety assessment of Uvaria chamae root extract: acute and subchronic toxicity studies. Biomed Environ Mass Spectrom 1988;15(8):413-417. While every effort has been made to describe these plants accurately, please keep in mind that height, bloom time, and color may differ in various climates. Canadian J Appl Sci. In this study, the aqueous leaf extract of Justicia carnea was used. Background: Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. Brazilian-plumeflowers are best propagated from softwood cuttings. 2018;2018:5762368. Colorimetric assay of catalase. Studies on the Phytochemical and Nutritional Composition of Aqueous Leaf Extract of Justicia Carnea and its Effect on Some Biochemical Parameters in Anaemic Rats. Acute toxicity was determined in two phases using Lorke method. J. Appl. OTHER NAME(S): Achille Millefeuille, Achille Mille-Feuille, Ana. Also present in the leaf extract are minerals (such as magnesium, copper, iron, zinc, calcium); and vitamins (such as vitamins A, C, E and B-vitamins). Generic and epigenetic contributions to human nutrition and health: managing genome-diet interactions. 2005 - 2023 WebMD LLC, an Internet Brands company. https://doi.org/10.4314/njps.v19i1.32627. A multidisciplinary overview of intoxicating snuff rituals in the western hemisphere. Star Apple: Amazing Health Benefits of eating its fruits. Packed cell volume (PCV) and mean corpuscular volume (MCV) in treated rats with JCEE were statistically unperturbed compared to the control. Ewe eje isn't capable of causing any side or negative effects if consumed moderately. Two of the most important soil considerations include fertility and drainage. Compared to the control, total protein in liver and kidney were statistically not altered except rats that were administered with 1200mg/kg JCEE that showed significant (p<0.05) decrease in the liver. Tropical habitats mean constant moisture. Deleting this collection CANNOT be undone. PubMedGoogle Scholar. The findings show that ethanol extracts of Costus afer and Justicia carnea could operate as main antioxidants and free radical scavengers. The weight of liver and kidney of rats were measured immediately after excising the organs and is presented in Table2. African J Plant Sci. Ewe eje isnt capable of causing any side or negative effects if consumed moderately. Accept When it comes to fertilizing, an NPK balance of 5-10-5 will work well, encouraging blooming and strong growth. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. In the kidney, SOD and MDA level were indistinguishable compared to the control except SOD level in rats that received 800mg/kg JCEE that reduced significantly (p<0.05). Local consumers of the leaves are mostly . 2). Feed the soil when the cutting is new to encourage better growth. Radhika J, Sathya S, Jothi G, Japasheba JL. We currently have no information for JUSTICIA PECTORALIS overview. This encourages better flowering and bushier and denser new growth. The principle is based on the reduction of dichromate in a weak acid medium (acetic acid) to chromic acetate which is further heated in the presence of hydrogen peroxide to form an unstable intermediate (perchromic acid) that can be monitored spectrophotometrically at 620nm. Mapanga RF, Musabayane CT. Exactly 1.0ml of tissues (liver and kidney) was deproteinised using 0.1ml of 10% TCA and centrifuged at 650g for 5min to obtain supernatant. This is attributed to the anti-hyperlipidaemic properties of the plant. The resultant liquid after boiling is usually crimson red. However, lowest (50mg/kg) dose of extract significantly elevated MCH and MCHC. Dyslipidemia is one of the risk factors of cardiovascular diseases. PubMed Oso BJ, Oyewo EB and Oladiji AT. Be sure to follow relevant directions on product labels and consult your, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Mediterranean, Low-Fat Diets Are Best for Heart Problems, Least Amount of Exercise You Need to Stay Healthy, Nerve 'Pulse' Therapy May Help Ease Sciatica, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. The absorbance was taken at interval of 1min for 3min at 480nm. The catalase activity was calculated using the expression: Note: A=change in absorbance, TV=total volume, TP=total protein, SV=sample volume, =molar extinction=40M1 cm1. PubMed B-vitamins are good sources of energy. The ameliorative effect of Justicia carnea on blood glucose level and lipid profile in alloxan-induced diabetic albino rats was evaluated in a study titled, "Effects of methanol leaves extract . When there is high cholesterol level in your blood, LDL- and VLDL- cholesterols are being deposited on the arterial wall of blood vessels, thereby blocking free flow of blood and increasing blood pressure. Clin Phytosci 2019; 5:9. https://doi.org/10.1186/s40816-019-0104-4. The leaves were able to greatly lower the total cholesterol, LDL-cholesterol, and triglyceride levels, but increased the serum level of high density lipoprotein (HDL) cholesterol. Influence of ethanolic extracts of dried fruit of Xylopia aethiopica (Dunal) A. Buege JA, Aust SD. It is obvious that Justicia carnea has potential antianemic, antioxidant, antidiabetic, hepatoprotective, and immune-boosting properties. 10.9734/ijbcrr/2020/v29i630194. J Afr Ass Physiol Sci. Filed in Biochemistry Project Topics, Current Projects by TMLT Editorials on September 22, 2020. 5. -Amylase binding-interaction with JCAE was also investigated using fluorescence spectroscopy and molecular docking. The leaves of Justicia carnea contains powerful antioxidant activities and phytochemical components that help reduce oxidative stress, and reduce the risk of development of cancer. Justicia pectoralis is a flowering herb that grows in tropical areas of the Americas, including South and Central America. Acta Sci Pol Technol Aliment. Details on Purple Shield plant care. How often should it be watered? Arch Toxicol. Google Scholar. Article This is why you should avoid potting them if you live in colder areas. Research reports it isnt capable of causing kidney and liver damage either but dont eat it raw. The unique flower clusters and bright coloring has made it a popular choice among landscape artists and amateur gardeners as well. 1978;90:819. What this means is that aside fighting anemia, justicia carnea leaves also improves your cardiovascular health by suppressing the tendency for dyslipidemia.

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side effect of justicia carnea