J Thorac Cardiovasc Surg. In: BMJ Clinical Evidence. None of the tissue sealants tested, however, increased the ultimate load to complete failure of the repair. 2017;25(1):145-149. K081635. Eligible children were enrolled and randomized, stratified by burn thickness, to be dressed in an ointment-based dressing or Mepitel Ag. Orthopedics. 2020;1-18. Amniotic tissues contain many regenerative cytokines, growth factors, and extracellular matrix molecules including proteoglycans, hyaluronic acid, and collagens I, III, and IV. The mean duration of days until coverage of the bone and/or tendon with granulation tissue was 36.14 (5.16 weeks) (range of 5 to 117 days). Hibner M, Castellanos ME, Drachman D, Balducci J. Repeat operation for treatment of persistent pudendal nerve entrapment after pudendal neurolysis. Clin Podiatr Med Surg. The two products are prescribed by a physician or other qualified health care professional and indicated for the management of wounds. Injectable skin fillers. J Spinal Cord Med. A randomized controlled clinical trial of a hypothermically stored amniotic membrane for use in diabetic foot ulcers. Long-term in vivo assessment of bioengineered skin substitutes:A clinical study. Garramone CE, Lam B. Arthroscopy. Rouleau G, Erickson LJ. Ann Surg. J Hand Surg Am. It comes in a single size configuration as a hexagon patch with 2.5 cm sides, 5.0 cm in diameter, and total surface area of 16 cm squared. Site-specific rectocele repair with dermal graft augmentation: Comparison of porcine dermal xenograft (Pelvicol) and human dermal allograft. AmnioRepair is a Human Cellular and Tissue Based Product (HCT/P) per 21 CFR Part 1271. . Commentary. 2013;34(5):611-613. J Oral Maxillofac Surg. 2005;41(5):837-843. Surg Obes Relat Dis. Surg Neurol Int. Strattice is used by surgeons as a surgically implanted soft tissue patch to reinforce a patient's soft tissue where weakness exists, and for the surgical repair of damaged or ruptured soft tissue, such as in hernia repair, open abdominal repairs and in breast reconstruction, post mastectomy. Evaluation of porcine dermal collagen (Permacol) used in abdominal wall reconstruction. Arch Dermatol. Efficacy of fibrin sealant (human) (Evicel) in rhinoplasty:A prospective, randomized, single-blind trial of the use of fibrin sealant in lateral osteotomy. J Bone Joint Surg Am. These researchers tried to optimize operating times beginning with the biopsy and, during digestion, preparing the receiving areas. 2008;20(5):111-116. Baltimore, MD: CMS; May 18, 2017. Chaby G, Senet P, Vaneau M, et al. UpToDate [online serial]. Arthroscopy. Abhinav K, Shaaban M, Raymond T, et al. Silver-coating technology was developed to prevent wound adhesion, limit nosocomial infection, control bacterial growth, and facilitate burn wound care through a silver-coated dressing material. Vitale MA, Taylor F, Ross M, Moran SL. Difficult-to-heal chronic venous partial and full-thickness ulcers of the lower extremity that have failed standard wound therapy of at least 4-weeks duration. Canadian Agency for Drugs and Technologies in Health (CADTH). Typically, one application is applied per wound; however, the product may be reapplied if necessary. Romanelli M, Dini V, Bertone MS. Randomized comparison of OASIS wound matrix versus moist wound dressing in the treatment of difficult-to-heal wounds of mixed arterial/venous etiology. A total of 82 patients were analyzed in 2 homogeneous groups. Hernia. Wu XL, Briggs L, Murrell GA. Intraoperative determinants of rotator cuff repair integrity: An analysis of 500 consecutive repairs. Ottawa, ON: Canadian Agency for Drugs and Technologies in Health (CADTH); 2010. Skin substitutes for treating chronic wounds. Int Wound J. 2006;(1):CD005082. J Plast Reconstr Aesthet Surg. Arthroscopic stabilization of acromioclavicular joint dislocation using the AC graftrope system. The establishment of 20 different human embryonic stem cell lines and subclones; a report on derivation, culture, characterisation and banking. Rockville, MD: FDA; August 14, 2002. Important options for the clinician. Abdominal wall reconstruction with dual layer cross-linked porcine dermal xenograft: The "Pork Sandwich" herniorraphy. J Reconstr Microsurg Open. Ostomy Wound Manage. Barber FA, McGarry JE, Herbert MA, Anderson RB. The use of an acellular porcine dermal collagen implant in the repair of complex abdominal wall defects:A European multicentre retrospective study. A comprehensive literature search was performed on PubMed, EBSCO Host, Embase, and SCOPUS. 2014;156(4):902-908. Adv Skin Wound Care. Open J Regen Med. Clinical trials of a biosynthetic temporary skin replacement, Dermagraft-Transitional Covering, compared with cryopreserved human cadaver skin for temporary coverage of excised burn wounds. The amputation rate in the treatment cohort was 41.7 % less than that of the control cohort at 20 weeks (0.9 % versus 1.5 %, respectively). 2014;12(4):296-303. 2010;221(4):365-372. Boston, MA:VATAP; 2003. 2007;(1):CD005486. Gapski R, Parks CA, Wang HL. The incidence of fungal wound infections and skin grafting was similar between the 2 groups. Reconstruction of the right atrium and superior vena cava with extracellular matrix. Current status in wound healing. 2009;9(8):623-629. 2013;4:26. Most notably, it will be used for wounds resulting from chronic diabetic foot ulcers. The duration of some therapies was relatively short, and all the topical oxygen therapy devices use different doses. It consists of nano-scale materials to provide a resorbable scaffolding to facilitate cell migration, revascularization, and soft tissue formation and reinforcement in the prepared wound bed. Specifically, the device processes a small, thin split-thickness skin sample 0.006-0.008 inch (0.15-0.20 mm) in depth to prepare an autologous Regenerative Epidermal Suspension (RES) for immediate delivery onto the wound surface. The investigators note that burn depth was assessed clinically only by experienced burn physicians. Surgery. Itani KM, Rosen M, Vargo D,et al. Unite Biomatrix differs from other products in that it is composed ofdecellularized equine pericardial implants. As the dressing material accumulates fluid, silver ions are released from the dressing into the wound environment. 2006;52(6):68-70, 72, 74 passim. 2017;224(3):341-350. Stepney, Australia: Australian Safety and Efficacy Register of New Interventional Procedures - Surgical (ASERNIP-S); August 2006. 2019a;16(1):19-29. This may have potentially skewed healing rates and wound duration measures towards SOC. Lower body mass index (BMI; p = 0.002) and non-plantar wounds (p = 0.009) were the only patient- or wound-related factors associated with complete healing at 6 months. Burns. J Surg Case Rep. 2013;2013(4). Dressings for acute and chronic wounds: A systematic review. Aetna Inc. and its subsidiary companies are not responsible or liable for the content, accuracy, or privacy practices of linked sites, or for products or services described on these sites. 2007;60(11):1214-1218. 2008;24(1):20-24. Romanelli M, Dini V, Bertone M, et al. 2005;76(11):1814-1822. Eur J Cardiothorac Surg. 2018;26(2):70-74. They searched MEDLINE, CINAHL, and the Cochrane Controlled Trials Registry Database to identify RCTs. 2009;2(2):67-72. Early report of a randomized comparative clinical trial of Strattice reconstructive tissue matrix to lightweight synthetic mesh in the repair of inguinal hernias. Acellular dermal matrix allograft: An effective adjunct to oronasal fistula repair in patients with cleft palate. Ann Plast Surg. Wu AY, Vagefi MR, Georgescu D, et al. 95-0652. and 5/box); and 10 cm x 15 cm (1 ea. Predictors of complications and comparison of outcomes using SurgiMend fetal bovine and AlloDerm human cadaveric acellular dermal matrices in. A prospective, randomised comparative study of weekly versus biweekly application of dehydrated human amnion/chorion membrane allograft in the management of diabetic foot ulcers. Two alternative dural sealing techniques in posterior fossa surgery: (Polylactide-co-glycolide) self-adhesive resorbable membrane versus polyethylene glycol hydrogel. An economic evaluation examining the cost effectiveness of continuous diffusion of oxygen therapy for individuals with diabetic foot ulcers. Baltimore, MD: CMS; July 7, 2021. SurgiMend Collagen Matrix (TEI Biosciences, Boston, MA) was cleared through the FDA 510(k) process in 2007. J Minim Invasive Gynecol. National Institute for Health and Care Excellence (NICE). Bell R, Desai S, House H,et al. Cipolla et al (2010) evaluated the effectiveness of fibrin glue in the prevention of seroma formation after axillary lymphadenectomy. InnovaMatrix AC is the first Food and Drug Administration cleared medical device sourced from pig placenta. Rockville, MD: FDA; March 19, 2008. 2018;6(5):e1763. Urology. Dermatol Surg. 2011;32(5):S545-S549. Ritz MC, Gallegos R, Canham MB, et al. 2008;87(1):56-63. Acellular dermal allograft for ventral hernia repair in the compromised surgical field. Restorigin amniotic fluid contains collagen substrates, growth factors, and cytokines (not an all-inclusive list). J Neurosurg. 2013;(7):CD009101. Female Pelvic Med Reconstr Surg. J Am Acad Dermatol. OMeara S, Cullum N, Majid M, Sheldon T. Systematic reviews of wound care management: (3) antimicrobial agents for chronic wounds; (4) diabetic foot ulceration. Driver VR, Hanft J, Fylling CP, Beriou JM; Autologel Diabetic Foot Ulcer Study Group. For the temporary wound covering for surgically excised full-thickness and deep partial-thickness thermal burn wounds in persons who require such a covering before autograft placement; For the treatment of mid-dermal to indeterminate depth burn wounds that typically require debridement and that may be expected to heal without autografting. A multicentre randomised controlled trial evaluating the efficacy of dehydrated human amnion/chorion membrane (EpiFix) allograft for the treatment of venous leg ulcers. There were 778 patients treated with the graft in the treatment cohort, who were paired with 778 patients drawn from a pool of 126,864 candidates treated with SOC alone (controls), by using propensity matching to create nearly identical cohorts. 2008;122(4):1206-1213. Madison, WI: Mallinckrodt; revised June 2021. Collective capabilities of XCelliStems composition include the following activities within the tissue: binding to existing native ECM material, binding to cells, signaling cell attraction, cell mobility, cell growth, and cell differentiation. Systematic reviews of wound care management: (2) dressings and topical agents used in the healing of chronic wounds. Hsu PW, Salgado CJ, Kent K, et al. 2006;12(9):2407-2424. Manning L, Ferreira IB, Gittings P, et al. Am J Sports Med. Thompson and colleagues (2019) conducted a prospective, randomized controlled trial comparing two treatments for diabetic foot ulcer: group A, total contact cast and human amniotic allograft versus group B, total contact cast and standard wound care. Int Braz J Urol. 2007;38 Suppl 5:S39-S45. A total of 15 patients with 15 wounds at a single hospital-based wound care center were included in the study; 11 wounds had exposed bone, 1 wound had exposed tendon, and 3 wounds had exposed bone and tendon. 2008;181(3):2103-10. Plast Reconstr Surg. Coccolini F, Lotti M, Bertoli P, et al. Reddy M. Pressure ulcers. Baltimore, MD: CMS January 1, 2022. TruSkin addresses biological deficiencies in the wound, assists in epithelialization, and aids in preserving surrounding tissue. Overview of the management of the severely burned patient. London, UK: NICE; November 2011. The MicroVas Vascular Treatment System. 2016;25(6):320-325. There was an increase from baseline to week 1 in transforming growth factor (TGF) (p =0.008), tumor necrosis factor (TNF) (p =0.014), vascular endothelial growth factor (VEGF) (p =0.008), platelet derived growth factor (PDGF) (p =0.087), and insulinlike growth factor1 (IGF1) (p =0.058); baseline to week 2 in TGF (p =0.010), VEGF (p =0.051), and interleukin-6 (IL6) (p =0.031); and baseline to week 3 with TGF (p =0.055) and IL6 (p =0.054). Am Surg. Niederauer MQ, Michalek JE, Armstrong DG. Arthroscopy. Beale EW, Hoxworth RE, Livingston EH, Trussler AP. A comparative histologic study. After cohort matching, this data-set was not large enough to conduct this type of sub-analysis; future real-world matched-cohort studies looking at timely surgical intervention and recidivism are needed. 2016;25(Sup10):S8-S17. ProgenaMatrix is applied directly to the wound bed after debridement of the wound site to remove necrotic debris, biofilm, and non-viable tissue. Early results using sterilized acellular human dermis (Neoform) in post-mastectomy tissue expander breast reconstruction. Venous ulceration, a relatively common manifestation of venous hypertension, is often refractory to conservative treatment and difficult to treat. Int Wound J. In a prospective, randomized multi-center, pilot study, these researchers examined the safety and effectiveness of ASCS combined with compression therapy compared with standard compression alone (Control) for the treatment of VLUs. 2015;23(6):891-900. 2008;51(10):1482-1487. It is similar to living skin equivalent (LSE) and provides a supply of living cells, fibroblasts and keratinocytes anda fully developed extracellular matrix (Snyder, et al., 2012). Ozgenel GY, Samli B, Ozcan M. Effects of human amniotic fluid on peritendinous adhesion formation and tendon healing after flexor tendon surgery in rabbits. Plast Reconstr Surg Glob Open. Revitalon allografts are supplied in a single-sized package and provided in the following sizes: 1 cm round dot, 2x2 cm, 4x4 cm, and 4x6 cm. Dressings and topical agents for surgical wounds healing by secondary intention. Successful treatment of non-healing wounds with Xelma(R). 2003;27(5):368-375. Hernia. 2007;33(8):946-957. This product is intended to function as a barrier ad provide protective coverage from the surrounding environment for acute and chronic wounds. RM-2017. Wallen J, Rao V. Extensive tricuspid valve repair after endocarditis using CorMatrix extracellular matrix. Effectiveness of an extracellular matrix graft (OASIS Wound Matrix) in the treatment of chronic leg ulcers: A randomized clinical trial. 2015;24(6):261-262, 264-267. The healing rate with the graft was better than SOC across multiple subsets, but the most significant improvement was noted in the worst wounds that had a duration of 90 to 179 days prior to treatment (p = 0.0073), exposed deep structures (p = 0.036), and/or Wagner grade-4 ulcers (p = 0.04). Lawin PB, Silverstein P, Still JM Jr. E-Z Derm a porcine heterograft material. Abdel-Fattah M, Barrington JW, Arunkalaivanan AS. Holmes JH, IV, Molnar JA, Carter JE, et al. Commercially available tissue sealants (Tisseel, Evicel, and DuraSeal), when used to augment 2-suture nerve repairs, as in the authors' protocol, help prevent this initial gapping. Diabet Med 1997;14:1010-1011. Finally, while these researchers conducted an exhaustive matching process to ensure the similarities between groups, all factors could not be measured. Chalmers RT, Darling Iii RC, Wingard JT,et al. Cell therapy for secondary osteonecrosis of the femoral condyles using the Cellect DBM System: A preliminary report. Culligan PJ, Littman PM, Salamon CG,et al. Hotta SS, Holohan TV. Aldehyde-treated porcine skin versus biobrane as biosynthetic skin substitutes for excised burn wounds: Case series and review of the literature. Anesth Analg. Neurosurgery. 2004;30(5):471-475. Rommer EA, Peric M, Wong A. Urinary bladder matrix for the treatment of recalcitrant nonhealing radiation wounds. The use of growth factors in clinical practice. J Am Coll Surg. Marston WA. The high failure rate of biologic resurfacing of the glenoid in young patients with glenohumeral arthritis. 2015;18(8):586-595. Zelen CM, Serena TE, Snyder RJ. J Foot Ankle Surg. World J Emerg Surg. The use of bovine pericardial strips on linear stapler to reduce extraluminal bleeding during laparoscopic gastric bypass: Prospective randomized clinical trial. Harding K, Sumner M, Cardinal M. A prospective, multicentre, randomised controlled study of human fibroblast-derived dermal substitute (Dermagraft) in patients with venous leg ulcers. Autologous platelet-rich plasma for treating chronic wounds. Bou Monsef J, Buckup J, Waldstein W,et al. #: OF1-000349-en-USVersion: FLanguage: EnglishRevision Date: 02/22/2023 2023 Coding and Reimbursement Guidelines for Autograft OATS TechniqueFile Type: Ref. Surgery. Diabetic foot problems: Inpatient management of diabetic foot problems (Draft). St. Paul, MN; Synovis; 2008. Use the current applicable CPT/HCPCS code(s). TransCyte provides a temporary protective barrier for the wound. Chauviere MV, Schutter RJ, Steigelman MB,et al. Limitations of the study include that it was retrospective and lacked a control group. 2000;135(6):627-634. Baltimore, MD: CMS;May 18, 2011. ACM Surgical Extra Advanced Collagen Powder, AlloDerm for protection of the carotid artery following radical neck dissection, AlloMax for indications other than breast reconstruction; forAlloMax for breast reconstruction(see, AmnioFill Human Placental Tissue Allograft, AmnioFix Amnion/Chorion Membrane Allograft, Amniomatrix Human Amniotic Suspension Allograft, Amniotic fluid injection for wound healing (including corneal wound healing) and for prevention of adhesions after orthopedic surgery, Amniox (human embryonic membrane) for tarsel tunnel repair and all other indications, Artelon (poly[urethane urea] elastomer) for anterior cruciate ligament reconstruction, rotator cuff repair, trapezio-metacarpal joint osteoarthritis and all other indications, Arthres GraftRope for acromio-clavicular joint separation reconstruction, Ascent (injectable derived from human amniotic fluid), Autologous blood-derived products (e.g., autologous platelet-rich plasma, autologous platelet gel, and autologous platelet-derived growth factors (e.g., Autologel, Procuren,SafeBlood), Autologous fat for the treatment of scars, Avotermin for improvement of skin scarring, BioFix Flow Placental Tissue Matrix Allograft, Biostat Biologx fibrin sealant for wound healing and all other indications, Biotape reinforcement matrix for soft tissue augmentation and all other indications, CellECT (human amnion and amniotic fluid allograft), CorMatrix ECMPatch for cardiac tissue repair and all other indications, Cortiva Allograft Dermis (for use in breast reconstructive surgery see, Cymetra injectable allograft for wound healing (see also, Dehydrated human amniotic membrane allograft (e.g., AmnioPro, BioFix and FlowerPatch), DermACELL, DermACELL AWM, and DermACELL AWM Porous for indications other than diabetic foot ulcers, DermaClose RC continuous external tissue expander for facilitation of wound closure and all other indications, Dermagraft for chronic foot ulcer secondary to necrotizing fasciitis, DermaMatrix (formerly InteXen) Porcine Dermal Matrixfor wound healing and other indications other than breast reconstruction; for DermaMatrix for breast reconstruction(see, Dermavest Human Placental Connective Tissue Matrix, DryFlex (human amnion allograft) for shoulder repair and all other indications, DuraGen Plus dural regeneration matrix for surgical repair of soft tissue deficiencies and all other indications, TransCu O2 (E02 Concepts, San Antonio, TX) continuous diffusion of oxygen (CDO) therapy for wound healing, EPIFLO transdermal continuous oxygen therapy for wound healing, Equine-derived decellularized collagen products (e.g., OrthADAPT, Unite, and Unite Biomatrix), EZ Derm for wound healing and all other indications, Evicel fibrin sealant for repair ofcerebrospinal fluidleakage and all other indications, FlexHD acellular dermal matrix for wound healing(for FlexHD for breast reconstruction, see, FloGraft Amniotic Fluid-Derived Allograft, GraftJacket Xpress injectable allograft for wound healing and all other indications, Human Health Factor 10 Amniotic Patch (HHF10-P), Hyalomatrix (hMatrix ADM) Tissue Reconstruction Matrix, Integra Wound Matrix and Integra Flowable Wound Matrix for the management of osteoradionecrosis of the jaw, wounds including partial and full-thickness wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunneled/undermined wounds, surgical wounds (e.g., donor sites/grafts, post-Mohs surgery, post-laser surgery, podiatric, wound dehiscence), trauma wounds (e.g., abrasions, lacerations, second-degree burns, skin tears) and draining wounds and all other indications, Jacob's Ladder external closure device for wound closure, Neoform Dermis for wound healing(for NeoForm for breast reconstruction, see, NeoPatch chorioamniotic membrane allograft, NuShield, NuShield Orthopaedics, andNuShield Spine, Oasis burn matrix for wound healing and all other indications, Omega3 MeriGen, Omega3 Wound ECM, Omega3 Wound Matrix (Kerecis fish skin graft), OrthADAPT Bioimplant (type I collagen scaffold) for tendon repair and all other indications, OviTex (reinforced tissue matrix) for ventral hernia repair, Parietex Composite (PCO) Mesh for the treatment of genito-urinary (e.g., uterine or vaginal vault) prolapse, Peri-Strips Dry, and Peri-Strips Dry with Veritas Collagen Matrix, Permacol Biologic Implant for soft tissue surgical repairs, including hernia repair, muscle flap reinforcement, rectal prolapse (including intussusception), rectocele repair, abdominal wall defects, plastic and reconstructive surgery, complex abdominal wall repair and all other indications, Plurivest Human Placental Connective Tissue Matrix, Porcine-derived decellularized collagen products (e.g., Collamend, Cuffpatch, Pelvicol, and Pelvisoft), Porcine-derived decellularized fetal skin products (e.g., Mediskin), Porcine-derived polypropylene composite wound dressing (e.g., Avaulta Plus), PRISMA matrix wound dressing for pressure ulcer, ProLayer human allograft acellular dermal matrix, PuraPly Antimicrobial Wound Matrix (PuraPly AM), Radiofrequency stimulation devices (e.g., Provant Wound Closure System, MicroVas Vascular Treatment System) for wound healing, RECELL Autologous Cell Harvesting Device (RECELL), ReNu (amniotic membrane and fluid allograft), Silver-coated wound dressings (e.g., Acticoat, Actisorb, Aquacel Ag, Granufoam silver VAC dressing, Mepitel Ag, and Silversorb) for wound healing andallother indications, Strattice Reconstructive Tissue Matrixfor wound healing(for Strattice for breast reconstruction see, SurgiMend for plastic and reconstructive surgery, muscle flap reinforcement, hernia repair, reinforcement of soft tissues repaired by sutures or suture anchors, during tendon repair surgery (including reinforcement of the rotator cuff, patellar, Achilles, biceps, quadriceps, or other tendons), and all other wound care indications(forSurgiMend for breast reconstruction, see, Surgisis (including Surgisis AFP Anal Fistula Plug, Surgisis Gold Hernia Repair Grafts, and Surgisis Biodesign) (see, TenoGlide tendon protector sheet (Tendon WrapTM tendon protector) for the management and protection of tendon injuries and all other indications, TenSIXAcellular Dermal Matrixfor tendon repair and all other indications, TheraForm Standard/Sheet Absorbable Collagen Membrane. Patients with functional loss of skin due to scarring may also be appropriate for treatment with SkinTE. Cervigni M, Natale F, La Penna C,et al. Transplantation of chronic wounds with epidermal sheets derived from autologous hair follicles--the Leipzig experience. A systematic review of silver-containing dressings and topical silver agents (used with dressings) for burn wounds. Int Wound J. Glat P, Orgill DP, Galiano R, et al. Reinforced biologic mesh reduces postoperative complications compared to biologic mesh after ventral hernia repair. Am J Clin Dermatol. 510(k) Summary. 2014;80(10):999-1002. 1995;16(3 Pt 1):331-333; discussion 333-334. 2010;56(6):24-31. Trop M, Novak M, Rodl S, et al. Semin Pediatr Surg. Drugs, Biologicals, and Radiopharmaceuticals. Br J Surg. Tissue Eng Part A. J Hand Surg Eur Vol. A total of 687 patients were included. Strauss EJ, Verma NN, Salata MJ,et al. J Foot Ankle Surg. naturally occurring, non-cross-linked extracellular matrix; completely resorbable; contains multiple naturally occurring growth factors; patients were followed for only 1 week following complete healing. Use of acellular dermal matrix for complicated ventral hernia repair: Does technique affect outcomes? User corrected segmentations are then propagated to neighboring time points. These investigators stated that a large RCT that examines changes in wound area reduction and cytokines in active and sham treatment groups would give clinicians better insights regarding the effect of continuous topical oxygen on and timing and the expression of cytokines. Outcomes of biosynthetic and synthetic mesh in ventral hernia repair. Treatment of a persistent iatrogenic cerebrospinal fluid-pleural fistula with a cadaveric dural-pleural graft. Dis Colon Rectum. Tettelbach W, Cazzell S, Reyzelman AM, et al. Newman MI, Baratta LG, Swartz K. Activated, type I collagen (CellerateRx) and its effectiveness in healing recalcitrant diabetic wounds:A case presentation. 1993;32(3):263-268. 2016;16:e10. Greco RM, Iocono JA, Ehrlich HP. IV. 2009;99:301-305. McCarthy CM, Lee CN, Halvorson EG,et al. Horizon Scanning Prioritising Summary - Volume 7. Meyer RA, Bagheri SC. J Card Surg. Favreau-Weltzer C, Bouchard D, Eleouet-Kaplan M, Pigot F. Response to Ratto et al., 'new Gore Bio-A() plug for anal fistula'. Database review of possible factors influencing point-of-care platelet gel manufacture. 2016;37(1):e90-e95. Hyaluronic acid in the treatment and prevention of skin diseases: molecular biological, pharmaceutical and clinical aspects. Randelli F, D'Anchise R, Ragone V,et al. Demonstration of the safety and effectiveness of the RECELL System combined with split-thickness meshed autografts for the reduction of donor skin to treat mixed-depth burn injuries. The quantity and size of the product used vary based upon wound size and physician recommendation. Stern R, McPherson M, Longaker MT. 2014;37(10):529-538. Podiatry Today. Diabetic Ulcer Study Group. The manufacturer states that TruSkin, an advanced skin substitute,is an easy-to-use, off-the-shelf alternative to fresh skin allograft. This short-term pilot study showed that injectable, flowable amniotic allografts can be used for orthopedic sports injuries of the lower extremities. AETMIS 06-08. 2005;16(3):349-356. Post-excision of donor sites, all donor sites were randomly covered either by amniotic membrane or conventional dressing such as gauze soaked with topical Vaseline.
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